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1 Department of Internal Medicine and Rheumatology, Sf. Maria Clinical Hospital, Bucharest, Romania
2Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
3Department of Thoracic Surgery, Sf. Maria Clinical Hospital, Bucharest, Romania
4Department of Histopathology, Sf. Maria Clinical Hospital, Bucharest, Romania
C Cobilinschi
, A Constantinescu, E Șargarovschi, S Enache, AR Bălănescu, D Opriș-Belinski
Abstract: Arthritis is an unusual manifestation of paraneoplastic syndrome, appearing in a variety of cancers, including pulmonary and colorectal. It can often pose a diagnostic challenge to physicians, since it may be difficult to distinguish from more commonly encountered rheumatic illnesses. Moreover, synchronous cancers are rare and unexpected in patients with symmetrical polyarthritis. Hypertrophic pulmonary osteoarthropathy is to be considered in patients with polyarthritis and lung neoplasia. The aim of this report is to highlight the case of a patient presenting with paraneoplastic polyarthritis, which led to identifying the presence of underlying synchronous lung and colorectal malignancies. Lymph node biopsy was performed raising suspicion of Caplan's syndrome but lung lobectomy confirmed adenocarcinoma. Rheumatologists should be reacquainted with rheumatic manifestations in malignant diseases.
Cite this article as: Cobilinschi C, Constantinescu A, Șargarovschi E, Enache S, Rodica Bălănescu A, Opriș-Belinski D. Paraneoplastic Polyarthritis in a Patient with Synchronous Lung and Colorectal Malignancy. Mediterr J Rheumatol 2023;34(3):363-6.
Article Submitted: 22 Nov 2022; Revised Form: 7 Feb 2023; Article Accepted: 23 Jun 2023; Available Online: 31 Aug 2023
https://doi.org/10.31138/mjr.20230831.pp
This work is licensed under a Creative Commons Attribution 4.0 International License.
©2023 The Author(s).
