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Mediterr J Rheumatol 2020;31(4):424-6
Interaction of Human Salivary Gland Epithelial Cells with B Lymphocytes: Implications in the Pathogenesis of Sjögren’s Syndrome
Authors Information
Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece

Athanasios Tzioufas, Efstathia K. Kapsogeorgou
References
  1. Tzioufas AG, Kapsogeorgou EK, Moutsopoulos HM. Pathogenesis of Sjogren's syndrome: What we know and what we should learn. J Autoimmun 2012 Aug;39(1-2):4-8.
  2. Christodoulou MI, Kapsogeorgou EK, Moutsopoulos HM. Characteristics of the minor salivary gland infiltrates in Sjogren's syndrome. J Autoimmun 2010;34:400-7.
  3. Christodoulou MI, Kapsogeorgou EK, Moutsopoulos NM, Moutsopoulos HM. Foxp3+ T-regulatory cells in Sjogren's syndrome: correlation with the grade of the autoimmune lesion and certain adverse prognostic factors. Am J Pathol 2008;173:1389-96.
  4. Kapsogeorgou EK, Christodoulou MI, Panagiotakos DB, Paikos S, Tassidou A, Tzioufas AG, et al. Minor salivary gland inflammatory lesions in Sjogren syndrome: do they evolve? J Rheumatol 2013;40:1566-71.
  5. Hansen A, Daridon C, Dorner T. What do we know about memory B cells in primary Sjogren's syndrome? Autoimmun Rev 2010;9:600-3.
  6. Kapsogeorgou EK, Manoussakis MN. Salivary gland epithelial cells (SGEC): carriers of exquisite B7-2 (CD86) costimulatory molecules. J Autoimmun 2011;35:188-91.
  7. Kapsogeorgou EK, Moutsopoulos HM, Manoussakis MN. Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4. J Immunol 2001;166:3107-13.
  8. Kapsogeorgou EK, Moutsopoulos HM, Manoussakis MN. A novel B7-2 (CD86) splice variant with a putative negative regulatory role. J Immunol 2008;180:3815-23.
  9. Daridon C, Devauchelle V, Hutin P, Le Berre R, Martins-Carvalho C, Bendaoud B, et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjogren's syndrome. Arthritis Rheum 2007;56:1134-44.
  10. Dimitriou ID, Kapsogeorgou EK, Moutsopoulos HM, Manoussakis MN. CD40 on salivary gland epithelial cells: high constitutive expression by cultured cells from Sjogren's syndrome patients indicating their intrinsic activation. Clin Exp Immunol 2002;127:386-92.
  11. Dimitriou ID, Kapsogeorgou EK, Abu-Helu RF, Moutsopoulos HM, Manoussakis MN. Establishment of a convenient system for the long-term culture and study of non-neoplastic human salivary gland epithelial cells. Eur J Oral Sci 2002;110:21-30.