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Volume 34, Issue 4, December 2023



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Mediterr J Rheumatol 2021;32(2):176-8
DNA Methylation Studies in Saliva of Patients with Sjögren’s Syndrome
Authors Information

Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece

References
  1. Konsta OD, Le Dantec C, Charras A, Cornec D, Kapsogeorgou EK, Tzioufas AG, et al. Defective DNA methylation in salivary gland epithelial acini from patients with Sjögren’s syndrome is associated with SSB gene expression, anti-SSB/LA detection, and lymphocyte infiltration. J Autoimmun 2016 Apr;68:30-8.
  2. Cole MB, Quach H, Quach D, Baker A, Taylor KE, Barcellos LF, et al. Epigenetic signatures of salivary gland inflammation in Sjögren’s syndrome. Arthritis Rheumatol 2016 Dec;68(12):2936-44.
  3. Miceli-Richard C, Wang-Renault SF, Boudaoud S, Busato F, Lallemand C, Bethune K, et al. Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren’s syndrome. Ann Rheum Dis 2016 May;75(5):933-40.
  4. Imgenberg-Kreuz J, Sandling JK, Almlöf JC, Nordlund J, Signér L, Norheim KB, et al. Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren’s syndrome reveals regulatory effects at interferon-induced genes. Ann Rheum Dis 2016 Nov;75(11):2029-36.
  5. Mavragani CP, Sagalovskiy I, Guo Q, Nezos A, Kapsogeorgou EK, Lu P, et al. Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease. Arthritis Rheumatol 2016 Nov;68(11):2686-96.
  6. Delaleu N, Mydel P, Kwee I, Brun JG, Jonsson MV, Jonsson R. High fidelity between saliva proteomics and the salivary glands’ biological state defines biomarker-signatures for primary Sjögren’s syndrome. Arthritis Rheumatol 2015 Apr;67(4):1084-95.